Samuel RM, Majd H, Richter M, et al, Ott M, Goodarzi H✝, Fattahi F✝ (2020). Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men. Cell Stem Cell 27:876-889. ✝ Co-corresponding authors

Zhu, X.G., Chudnovskiy, A., Baudrier, L. et al, Goodarzi H, and Birsoy K (2020). Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells. Cell Metab

Tavora, B., Mederer, T., Wessel, K.J. et al, Goodarzi H, and Tavazoie SF (2020). Tumoural activation of TLR3–SLIT2 axis in endothelium drives metastasis. Nature 586:299-304.

Yu J, Naviskas A, Asgharian H, Culbertson B, Fish L, Garcia K, Olegario JP, Dermit M, Dodel M, Hanisch B, Liu Y, Weinberg EM, Dienstmann R, Warren RS, Mardakheh F, and Goodarzi H (2020). RBMS1 suppresses colon cancer metastasis through targeted stabilization of its mRNA regulon. Cancer Disc 10:1410–23

Fish L, Navickas A, Culbertson B, Xu Y, Nguyen HCB, Zhang S, Hochman M, Okimoto R, Dill BD, Molina H, Najafabadi HS, Alarcon C, Ruggero D, and Goodarzi H (2019). Nuclear TARBP2 Drives Oncogenic Dysregulation of RNA Splicing and Decay. Mol Cell 75(5), 967-81.

Litterman AJ, Kageyama R, Le Tonqueze O, Zhao W, Gagnon JD, Goodarzi H, Erle D, and Ansel M (2019). A massively parallel 3′ UTR reporter assay reveals relationships between nucleotide content, sequence conservation, and mRNA destabilization. Genome Res doi:10.1101/gr.242552.118.

Mauer J, Sindelar M, Despic V, Guez T, Hawley BR, Vasseur J, Rentmeister A, Gross S, Pellizzoni L, Debart F, Goodarzi H, Jaffrey S (2019). FTO controls reversible m6Am RNA methylation during snRNA biogenesis. Nature Chem Biol 15, 340–347.

Fish L, Zhang S, Yu J, Culbertson B, Zhou A, Goga A, Goodarzi H (2018). Cancer cells exploit an orphan RNA to drive metastatic progression. Nature Med 24, 1743-51.

Huh D, Passarelli MC, Fish L, Molina H, McMillan EA, Goodarzi H, and Tavazoie SF (2018). An adaptive stress-induced tRNA depletion response mediates codon-based gene repression and growth suppression. BioRxiv.

Knott SRV, Wagenblast E, Khan S, et al., Goodarzi H, Poulogiannis G, Hannon G (2018). Asparagine bioavailability governs metastasis in a model of breast cancer. Nature 554:378–381.

Alkallas R, Fish L, Goodarzi H, Najafabadi HS (2017). Inference of RNA decay rate from transcriptional profiling highlights the regulatory programs of Alzheimer’s disease. Nature Comm 8: 909.

Goodarzi H (2017). Charting the “unknown unknowns” of cancer progression. Sci Transl Med 9 (400), eaao0959.

Kingham PT, Nguyen CB, Zheng J, Konstantinidis IT, Sadot E, Shia J, Kuk D, Zhang S, Saltz L, D’Angelica M, Jarnagin WR, Goodarzi H✝, Tavazoie SF✝ (2016). MicroRNA-203 predicts human survival after resection of colorectal liver metastasis. Oncotarget 8:18821-31. ✝ Co-corresponding authors

Goodarzi H*✝, Nguyen HCB, Zhang S, Dill BD, Molina H, Tavazoie SF✝ (2016). Modulated expression of specific tRNAs drives gene expression and cancer progression. Cell 165, 1416-1427. *Contributed equally; ✝ Co-corresponding authors

Lee H, Goodarzi H, Tavazoie SF, Alarcon CR (2016). TMEM2 Is a SOX4-Regulated Gene That Mediates Metastatic Migration and Invasion in Breast Cancer. Cancer Res 76(17):4994-5005.

Hwang HW, Park CY, Goodarzi H, Fak JJ, Mele A, Moore MJ, Saito Y, Darnell RB (2016). PAPERCLIP Identifies MicroRNA Targets and a Role of CstF64/64tau in Promoting Non-canonical poly(A) Site Usage. Cell Rep 15(2):423-435.

Nguyen A, Yoshida M, Goodarzi H, Tavazoie SF (2016). Highly variable cancer subpopulations that exhibit enhanced transcriptome variability and metastatic fitness. Nature Comm 7: 11246.

Fish L, Pencheva N*, Goodarzi H*, Tran H, Yoshida M, Tavazoie SF (2016). Muscleblind-like 1 suppresses breast cancer metastatic colonization and stabilizes metastasis suppressor transcripts. Genes & Dev 30: 386-398. *Contributed equally


Alarcon C, Goodarzi H, Lee H, Liu X, Tavazoie S, Tavazoie SF (2015). HNRNPA2B1 Is a Mediator of m6A-Dependent Nuclear RNA Processing Events. Cell 162: 1299-1308.

Goodarzi H, Liu X, Nguyen HCB, Fish L, Tavazoie SF (2015). Endogenous tRNA-Derived Fragments Suppress Breast Cancer Progression via YBX1 Displacement. Cell 161: 790-802.

Furlow PW, Zhang S, Soong ST, Halberg N, Goodarzi H, Mangrum C, Wu G, Elemento O, Tavazoie S (2015). Mechanosensitive pannexin-1 channels mediate microvascular metastatic cell survival. Nature Cell Bio 17, 943-952.

Alarcon CR, Lee H*, Goodarzi H*, Halberg N, Tavazoie S (2015). N6-methyladenosine marks primary microRNAs for processing. Nature 519, 482-485. *Contributed equally

Goodarzi H, Zhang S, Buss CG, Fish L, Tavazoie S, Tavazoie SF (2014). Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins. Nature 513, 255-260

Oikonomou P*, Goodarzi H*, Tavazoie S (2014). Systematic Identification of Regulatory Elements in Conserved 3? UTRs of Human Transcripts. Cell Reports 7(1): 281-292. *Contributed equally

Freddolino PL*, Goodarzi H*, Tavazoie S (2013). Revealing the genetic basis of natural bacterial phenotypic divergence. J. Bacteriol. doi:10.1128/JB.01039-13 *Contributed equally

Chiu IM, Morimoto ETA, Goodarzi H, et al., Tavazoie S, Myers RM, Maniatis T (2013). A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model. Cell Reports 4(2): 385-401

Freddolino PL*, Goodarzi H*, Tavazoie S (2012). Fitness landscape transformation through a single amino acid change in the Rho terminator. PLoS Genetics Vol. 8, e1002744. *Contributed equally

Goodarzi H, Najafabadi HS, Oikonomou P, Greco TM, Fish L, Salavati R, Cristea IM, Tavazoie S (2012). Systematic discovery of structural elements governing stability of mammalian messenger RNAs. Nature 485, 264-268.


Korpal M, Ell BJ, Buffa FM, Ibrahim T, Blanco MA, Celia-Terrassa T, Mercatali L, Khan Z, Goodarzi H, et al. (2011). Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization. Nature Med 17(9):1048-9.

Goodarzi H, Bennet BD, et al. (2010). Regulatory and metabolic rewiring during laboratory evolution of ethanol tolerance in E. coli. Mol Syst Biol 6:278.

Goodarzi H*, Elemento O*, Tavazoie S (2009). Revealing Global Regulatory Perturbations across Human Cancers. Mol Cell 36:900-11. *contributed equally

Najafabadi HS*, Goodarzi H*, Salavati R (2009). Universal function-specificity of codon usage. Nucl Acids Res 37(21):7014-7023. *contributed equally

Goodarzi H, Hottes AK, Tavazoie S (2009). Global discovery of adaptive mutations. Nat Methods 6(8):581-3.

Amini S, Goodarzi H, Tavazoie S (2009). Genetic dissection of an exogenously induced biofilm in laboratory and clinical isolates of E. coli. PLoS Pathogens 5:e1000432.

Goodarzi H, Torabi N, Najafabadi HS, Archetti M (2008). Amino acid and codon usage profiles: adaptive changes in the frequency of amino acids and codons. Gene 407(1-2):30-41.

Elahi E, Shafaghati Y, Asadi S, Absalan F, Goodarzi H, et al. (2007). Intragenic SNP haplotypes associated with 84dup18 mutation in TNFRSF11A in four FEO pedigrees suggest three independent origins for this mutation. J Bone Miner Metab 25(3):159-64.

Goodarzi H, Katanforoush A, Torabi N, Najafabadi HS (2007). Solvent accessibility, residue charge and residue volume, the three ingredients of a robust amino acid substitution matrix. J Theor Biol 245(4):715-25.

Torabi N, Goodarzi H, Shateri Najafabadi H. (2007). The case for an error minimizing set of coding amino acids. J Theor Biol 244(4):737-44.


Najafabadi HS, Goodarzi H, Torabi N, Banihosseini SS.(2006). Applying a neural network to predict the thermodynamic parameters for an expanded nearest-neighbor model. J Theor Biol 238(3):657-65.

Marashi SA, Goodarzi H, Sadeghi M, Eslahchi C, Pezeshk H (2006). Importance of RNA secondary structure information for yeast donor and acceptor splice site predictions by neural networks. Comput Biol Chem 30(1):50-7.

Goodarzi H, Shateri Najafabadi H, Torabi N (2005). On the coevolution of genes and genetic code. Gene 362:133-40.

Najafabadi HS, Goodarzi H, Torabi N (2005). Optimality of codon usage in Escherichia coli due to load minimization. J Theor Biol 237(2):203-9.

Goodarzi H, Najafabadi HS, Hassani K, Nejad HA, Torabi N (2005). On the optimality of the genetic code, with the consideration of coevolution theory by comparison of prominent cost measure matrices. J Theor Biol 235(3):318-25.

Goodarzi H, Shateri Najafabadi H, Torabi N (2005). Designing a neural network for the constraint optimization of the fitness functions devised based on the load minimization of the genetic code. Biosystems 81(2):91-100.

Goodarzi H, Nejad HA, Torabi N (2005). On the optimality of the genetic code, with the consideration of termination codons. Biosystems 77(1-3):163-73.

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